Application Development Illustration

DBHi brings together a variety of data integration analysts and programmers to carry out grant-funded research and development of novel software tools for data-intensive biomedical research.

"Harvest" Program: Integrated Research Databases

DBHi's Harvest program develops tools for building biomedical data discovery applications. Designed by and for biomedical researchers, the Harvest platform offers an elegant web-based interface for integrating, discovering and reporting on data integrated from multiple clinical and research-based sources.

  • Integration of genomic, imaging, research, and clinical endpoints
  • Dynamic query engine with visualizations
  • Hypothesis-driven exploration of data

"Care Assistant" Program: EHR Prompts, Interventions, and Decision Support

DBHi’s Care Assistant program uses web-based software and well-governed, protocol-driven research methods to develop and evaluate clinical decision support and other interventions delivered through the EHR.

Biorepository Portal Toolkit

Designed with the modern biorepository in mind, the Biorepository Toolkit integrates key system components in a user-friendly interface to protect subject privacy, asynchronously collect data and deeply annotate growing institutional specimen, data and genomic repositories by integrating familiar tools.

The Biorepository Portal (BRP) is a federated web application originally designed to support longitudinal biospecimen collection activities. Using HTTP protocols, it interfaces with downstream data systems, including REDCap and Thermo Fisher Scientific's Nautilus LIMS, to provide a single unified interface for data collection and update activities. An electronic honest broker (eHB) ensures longitudinal data collection is performed in a manner compliant with NCI Best Practices for Biospecimen Resources.

The Children’s Hospital of Philadelphia (CHOP) Department of Biomedical and Health Informatics (DBHi) developed an open-source informatics infrastructure to support data-intensive longitudinal biorepository studies.

Benefits of using the BRP Toolkit include:

  • De-identification and re-identification of subjects on-the-fly.
  • Creation and addition of records in multiple research systems to ensure patient privacy.
  • A longitudinally updated specimen and data resource that enables more flexible non-human subjects research.

For participating institutions or CHOP specimen and clinical data entry, access the biorepository portal.

Mobile Health Application Development Program

DBHi views mobile technologies as important tools that have great potential to improve the quality of care of our pediatric population.

Visit DBHi's mobile health application gateway to review our currently available apps.

Resource Informatics Programs

DBHi's vision is for centralized, well-governed access to integrated clinical and research data and samples. To that end, the Application Development group is implementing multiple integrated data collection and management systems to support the Research Institute:

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