Despite proven health benefits, human papillomavirus (HPV) vaccination rates are among the lowest of all routine immunizations. No previous large-scale trial has compared the benefit of automated decision support directed at clinicians, families, or both in any context.

We found that a clinician-focused intervention was most effective for initiating the HPV vaccine series, whereas a family-focused intervention supported completion. Decision support directed at both clinicians and families most effectively promotes HPV vaccine series receipt.

The article's lead author is Dr. Alexander Fiks, Co-Medical Director, CHOP Pediatric Research Consortium (PeRC).

CBMi's Dr. Robert Grundmeier, Dean Karavite and James Massey also contributed to the article which appeared in the June issue of Pediatrics.

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